As such anyone can take part in the chanting without any previous qualification. This chanting of 'Hare Krishna, Hare Krishna, Krishna Krishna, Hare Hare / Hare Rama, Hare Rama, Rama Rama, Hare Hare' is directly enacted from the spiritual platform, and thus this sound vibration surpasses all lower strata of consciousness – namely sensual, mental, and intellectual.

When we hear the transcendental vibration, this consciousness is revived. Krishna consciousness is not an artificial imposition on the mind this consciousness is the original energy of the living entity. Bhaktivedanta Swami describes the process of chanting the Maha Mantra as follows: 'Rama can also be a shortened form of Balarama, Krishna's first expansion.' The mantra is repeated, either sung out loud ( bhajan), congregationally ( kirtan), or to oneself aloud or mentally on prayer beads made of Tulasi ( japa). The more common interpretation is that Rāma refers to Rama of the Ramayana, an earlier avatar of Krishna. It is sometimes believed that 'Rama' in 'Hare Rama' means ' Radharamana' or the beloved of Radha (another name for Kṛṣṇa).

In the hymn Vishnu Sahasranama spoken by Bhishma in praise of Krishna after the Kurukshetra War, Krishna is also called Rama. Bhaktivedanta Swami Prabhupada, Harā refers to 'the energy/shakti of Supreme Personality of Godhead' while Krishna and Rama refer to Supreme Godhead Himself, meaning 'He who is All-Attractive' and 'He who is the Source of All Pleasure'. Another interpretation is as the vocative of Harā, a name of Rādhā, Krishna's eternal consort or His energy (Krishna's Shakti). 'Hare' can be interpreted as either the vocative form of Hari, another name of Vishnu meaning 'he who removes illusion'.

Sanskrit is a polysemic language and as such, this mantra has multiple interpretations all of which may be considered as correct.

Morning krishna bhajan